Massachusetts State Police said a crash on Interstate 495 in Westborough caused injuries and impacted traffic late Thursday afternoon.
Police said in a tweet around 4 p.m. that the right lane and breakdown lane of I-495 southbound were closed after the crash, which took place near the Massachusetts Turnpike.
Police said shortly after 6 p.m. that all lanes had reopened.
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From photos taken at the scene, a tractor-trailer appeared to have crashed through the guardrail. Another vehicle was wedged between the rail and the truck.
Authorities confirmed there were injuries in the crash, but no further details were immediately available.