The New England Patriots lead the AFC East for the first time this season after downing the Buffalo Bills 37-22.
Both teams boasted 3-2 records going into Week 6.
Tom Brady threw for 361 yards and four touchdowns in the victory. He completed 27 of 37 pass attempts. Three of his targets - Brandon LaFell, Rob Gronkowski and Julian Edelman - received more than 90 yards.
LaFell had two touchdowns. Brian Tyms and Tim Wright each had one.
Safety Patrick Chung came alive with nine tackles, and defensive end Rob Ninkovich sacked Bills quarterback Kyle Orton three times.