Down syndrome April 23, 2021 1:58 pm Meet Mikayla Holmgren Twenty-six-year-old Mikayla Holmgren has already made history, being the first woman with Down syndrome to compete in a Miss USA pageant, and she has her sights set on other big dreams. US & World Videos 4:04 Afternoon clouds over the region on Saturday 0:39 Police respond to incident in Whitinsville 2:15 Prince William and Kate Middleton ‘going through hell,' friend claims (report) 8:01 Lady Gaga's outfit changes, Rihanna's bold looks and more iconic Met Gala moments 20:35 Jurors in Karen Read trial visit site of John O'Keefe's death