A Russian ex-spy and his daughter fighting for their lives in an English hospital were attacked with a nerve agent in a targeted murder attempt, British police said Wednesday.
The case has further strained relations between Russia and Britain, which has said it will respond strongly if the Russian government is linked to the attack. It has overtones of a 2006 fatal attack on a former Russian spy that was blamed on the Kremlin.
In that incident, a radioactive poison was used. The choice of a nerve agent in the latest case follows the use of the banned nerve agent VX to kill the estranged half-brother of North Korea's leader last year.
Sergei Skripal, 66, and his 33-year-old daughter Yulia were found unconscious on a bench in the southwestern English city of Salisbury on Sunday, triggering a police investigation led by counterterrorism detectives. Baffled police initially said the pair had come into contact with an unknown substance.
"Having established that a nerve agent is the cause of the symptoms leading us to treat this as attempted murder, I can also confirm that we believe that the two people who became unwell were targeted specifically," Metropolitan Police counterterrorism chief Mark Rowley said.
Police said the two "remain in a critical condition in intensive care after being exposed to the substance."
Police have declined to speculate on who might be behind the attack. The Russian government has denied any involvement in the attack on Skripal, a former Russian agent who had served jail time in his homeland for spying for Britain before being freed in a spy swap.
Rowley said a police officer who treated Skripal and his daughter at the scene was in serious condition. He did not provide the officer's name or specifics about his condition.
Rowley didn't say what nerve agent was suspected in the attack. Nerve agents are chemicals that disrupt the messages sent by from the nerves to the body's organs. They can be administered in gas or liquid form, causing symptoms including vomiting, breathlessness, paralysis and often death. Officials have not offered a prognosis for Skripal and his daughter.
Sally Davies, the chief medical officer for England, said there was a low risk to the public.
Police and forensics officers continued to scour several sites in and around Salisbury on Wednesday. Police kept residents away from an Italian restaurant and a pub in the city, and cordoned off part of a business park about nine miles (14 kilometers) away, near the ancient stone monument of Stonehenge. Detectives appealed for information from anyone who visited either the Zizzi restaurant or the Bishop's Mill pub in Salisbury on Sunday.
Residents saw their usually placid town, famed for its 13th-century Gothic cathedral, turned into the center of a criminal probe with Cold War echoes.
With nerves still on edge, ambulances and emergency vehicles rushed to a building beside the Zizzi restaurant, which remains cordoned off. Witness Toni Walker said emergency services escorted two women from the building. Police and ambulance services declined to comment and it wasn't immediately clear if the incident had anything to do with the ongoing investigation.
Home Secretary Amber Rudd chaired a meeting of the government's emergency committee, known as Cobra, to discuss the investigation, which is now in the hands of counterterrorism police.
"We need to keep a cool head and make sure we collect all the evidence we can," Rudd said. "And then we need to decide what action to take."
Moscow officials, angered by allegations of Russian state involvement, accused Britain of using the case to fuel an "anti-Russian campaign" and further damage ties with Britain.
"What happened to Skripal has been immediately used to further incite an anti-Russian campaign in Western media," said Russian Foreign Ministry spokeswoman Maria Zakharova.
Skripal, a former colonel in Russia's GRU military intelligence service, was convicted in 2006 of spying for Britain and imprisoned. He was freed in 2010 as part of a widely publicized spy swap in which the U.S. agreed to hand over 10 members of a Russian sleeper cell found operating in America in return for four Russians convicted of spying for the West.
He and his daughter were found collapsed on a bench near a shopping mall Sunday in Salisbury, 90 miles (145 kilometers) southwest of London.
Foreign Secretary Boris Johnson told lawmakers Tuesday that if Moscow is shown to have been involved, the government would act — possibly downgrading England's participation in this year's soccer World Cup in Russia.
While police say they are keeping an open mind about the case, it has reminded many in Britain of the 2006 poisoning of former spy Alexander Litvinenko.
A British inquiry into his death found that Russian agents poisoned him by lacing his tea with radioactive polonium-210 and that the killing was probably approved by Russian President Vladimir Putin. Russia has denied any involvement in the Litvinenko case, and refused a request by Britain to extradite his accused killers.
Litvinenko's widow, Marina, wrote Wednesday in the Times of London that her husband's killing made clear to Britain's emergency services that they need to act quickly when "someone suddenly falls mysteriously ill."
"I am happy my story has raised awareness about the potential danger posed by Moscow, and this could help to save somebody's life," she wrote in an opinion piece.