More than 6,200 cyclists will ride in this weekend's Pan-Mass Challenge, a two-day, 192-mile ride across Massachusetts to raise money for the Dana-Farber Cancer Institute.
The goal this year is to raise $48 million for cancer research and patient care. If that amount is raised, it would bring the PMC's 38-year contribution to Dana-Farber to more than $595 million.
The ride kicks off Saturday in Sturbridge, continues east through Massachusetts and ends at the finish line in Providence, Rhode Island on Sunday.
Riders commit to raise between $500 and $7,800. Funds raised by the PMC account for more than 52 percent of the annual revenue of the Jimmy Fund, Dana-Farber's fundraising arm.
Many of the riders and volunteers are cancer survivors or current patients.