The Celtics cruised to victory Thursday and will travel to Indiana with a 2-0 lead in the Eastern Conference Finals.
The Pacers finished the first quarter with a 2-point lead, but the Celtics soon took control on their way to a 126-110 victory in Game 2.
Jaylen Brown put up 40 points in the win. Jayson Tatum and Derrick White each scored 23.
To make matters worse for Indiana, All-Star point guard Tyrese Haliburton exited in the third quarter with an apparent injury. He left with just 10 points.
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Pascal Siakam led the Pacers with 28 points, but it wasn't enough to keep up with Boston.
The C's will look to extend their lead Saturday night in Indianapolis.